ITR Laboratories Canada offers a full range of GLP compliant bioassay services to support the needs of non-clinical pharmaceutical development. Matrices routinely utilized include; urine, whole blood, plasma, serum, cerebral spinal fluid, aqueous/vitreous humor, and tissue extracts.

Methodologies currently implemented include by LC-MS-MS, HPLC, or ligand binding assay ligand binding assays, cell based assays and flow cytometry.

FULLY GLP COMPLIANT DATASETS SUPPORT:

  • Method development and validation for GLP application
  • Analysis of pharmacokinetics and biodistribution
  • Immunogenicity assays for detection of anti-drug antibodies and assessment of neutralizing activity

EQUIPMENT INCLUDES:

  • API 4000 Triple Quadrupoles LC-MS-MS
  • Various plate readers
  • ViiA7 QPCR